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Friday, March 30, 2018

The following is my comment today on a YouTube myeloma  survivor video:

    In the case of multiple myeloma,  there is an incredible amount of new research.   There are so many new treatments that are extending lifespans, although the talk of cure is an exaggeration.  Current treatments only seem to kill the mature myeloma cell and not the progenitor cells which eventually bring back the disease once the immune system looses control and the treatment is stopped or ceases to work. The most promising FDA approved treatment at the moment in terms of hazard risk is an antibody infusion of Daratumumab, which unleashes the patient's immune system against the disease.  It probably needs to be combined with an  HDAC6 inhibitor to be most effective.  HDAC6 inhibitors increase the number of CD38 receptors on myeloma cells while the do not effect the CD38 expression on lymphocytes.  Eating pancreas glandulars has the opposite effect on myeloma cells.  So, that is probably the worst thing to eat while undergoing Daratumumab treatment. 

    Many foods effective against cancer are so, because they are HDAC inhibitors. The most promising chemical in food for controlling the disease is emodin although you find no information about it outside research papers.  The worst nutrient for people with the disease is probably hyaluronic acid, since that is what researchers now use to grow the disease in the lab. The best source of information is possibly Google Scholar working back from present to the past.  The biggest problem with advice and information is that it is out of date and now known to be false. This comment is not intended as medical advice, but an attempt the stir ones curiosity about all the options for treating the disease.   Of the incurable cancers, multiple myeloma is considered to be one of the most treatable.

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